Persistent unexplained congenital clitoromegaly in females born extremely prematurely

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Persistent unexplained congenital clitoromegaly in females born extremely prematurely

OBJECTIVE Unexplained clitoromegaly is a rare but well recognised feature in girls born premature. Although detected at birth, girls may re-present during childhood to paediatric urologists and gynaecologists who should be aware of this condition. The aim of the study was to describe the clinical findings and management of a series of girls presenting with persistent congenital clitoromegaly as...

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Congenital adrenal hyperplasia causing clitoromegaly.

Congenital Adrenal Hyperplasia (CAH) is caused by congenital insufficiency of the enzyme 21 - hydroxylase (21-OHD) in the cortisol synthesis pathway. Because of the virilizing effects of androgens over-production, affected girls develop clitoral hypertrophy. Three patients with CAH are discussed below along with their surgical management and follow-up.

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Laterality in Prematurely -born Children1

The study examined the relationship between perinatal stress and decreased right handedness and decreased left cerebral dominance for speech with 215 children born prematurely, followed from birth, and tested at age 5. Results indicated that neither hand preference nor hand performance correlated with degree of perinatal stress and that eye preference was associated with perinatal stress though...

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Pain sensitivity in prematurely born adolescents.

BACKGROUND Several studies reported that preterm infants were found to be hypersensitive to pain. However, longitudinal and quantitative assessments of subsequent pain thresholds in adolescence are scarce. OBJECTIVE To assess the tenderness threshold in adolescents born prematurely compared with matched children born at full term. DESIGN Case-control study. SETTING Children in the communi...

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Hib vaccination in infants born prematurely.

AIMS To document the immunogenicity and persistence of antibody to polyribosyl-ribitol phosphate (PRP) as well as the clinical protection against invasive Haemophilus influenzae type b (Hib) disease in premature infants immunised at the routine schedule. METHODS Blood was obtained at 2, 5, 12, and 64 months of age from a cohort of prematurely born infants (<or=32 weeks gestation). Anti-PRP an...

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ژورنال

عنوان ژورنال: Journal of Pediatric Urology

سال: 2013

ISSN: 1477-5131

DOI: 10.1016/j.jpurol.2013.03.001